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Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular modeling techniques that improve the overall process of discovery and development by removing empiricism. The concept of developability involves making rational choices at the pre-clinical stages of biopharmaceutical drug development that could positively impact clinical outcomes. The book also addresses a general lack of awareness of the many different contributions that computation can make to biopharmaceutical drug development. This informative and practical reference is a valuable resource for professionals engaged in industrial research and development, scientists working with regulatory agencies, and pharmacy, medicine, and life science students and educators. It focuses primarily on the developability of monoclonal antibody candidates, but the principles described can also be extended to other modalities such as recombinant proteins, fusion proteins, antibody drug conjugates and vaccines. The book is organized into two sections. The first discusses principles and applications of computational approaches toward discovering and developing biopharmaceutical drugs. The second presents best practices in developability assessments of early-stage biopharmaceutical drug candidates. In addition to raising awareness of the promise of computational research, this book also discusses solutions required to improve the success rate of translating biologic drug candidates into products available in the clinic. As such, it is a rich source of information on current principles and practices as well as a starting point for finding innovative applications of computation towards biopharmaceutical drug development. Developability of Biotherapeutics: Computational Developability of Biotherapeutics: Computational Approaches of Biotherapeutics: Computational Approaches Edited by Developability of Biotherapeutics: DEVELOPABILITY OF BIOTHERAPEUTICS - CRCnetBASE DEVELOPABILITY OF BIOTHERAPEUTICS Chapter 10 Developability Assessment Workflows to describes applications of computational approaches toward discovery and Developability of Biotherapeutics: Computational Approaches Developability of Biotherapeutics: Computational Approaches presents the most extensive and systematic overview to date Developability of Biotherapeutics: Developability Of Biotherapeutics: Computational Approaches Developability Of Biotherapeutics: Computational Approaches Developability of Biotherapeutics: It focuses primarily on the developability of monoclonal Developability of Biotherapeutics: Computational Approaches Developability of Biotherapeutics: Computational Approaches by Sandeep Kumar Satish Kumar Singh2015 ISBN: 1482246139 Developability of Biotherapeutics: Developability of Biotherapeutics: Computational Approaches Developability of Biotherapeutics: Computational Approaches Developability of Biotherapeutics: The concept of developability involves making rational Developability of biotherapeutics : computational approaches Developability of biotherapeutics : computational approaches worldcatorg/oclc/930017843 Developability of biotherapeutics : Developability Developability of Biotherapeutics: Computational Developability of Biotherapeutics: Computational Approaches Developability of Biotherapeutics: working on computational modeling and developability Developability of Biotherapeutics: Computational 2016 Developability of Biotherapeutics: Computational Approaches - Original Biotherapeutics: Computational Approaches Developability of Biotherapeutics: Developability of Biotherapeutics: Computational Developability of Biotherapeutics: Computational Approaches biotherapeutics: computational approaches to improve peptide developability and
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